There are very few things on this earth that will really set me off and annoy the hell out of me. Cultural indifference would be one of the biggest ones, as well as sheer insensitivity to what other people are going through. I don't understand why there are people who are just totally incapable of picking up when, or why another person is incensed about something. It reeks of indifference, apathy and total selfishness. Granted of course that people obviously react differently to given situations, you'd think it to be wise (or smart really) to just be sensitive enough to the situation and to the person.